CDPH Mumps Testing Recommendations

Posted on: September 2, 2015

Since January 2015, 130 cases of mumps have been reported in Illinois. The majority of these cases have been associated with an outbreak at the University of Illinois at Urbana-Champaign (UIUC). In Chicago, seven cases of mumps have been reported this year; two among UIUC students. The Chicago Department of Public Health reminds providers that previously vaccinated individuals may not have detectable mumps IgM antibody regardless of timing of specimen collection, resulting in false-negative serology. For individuals with symptoms suggestive of mumps who have previously received the measles, mumps, rubella (MMR) vaccine, the preferred diagnostic test is real-time reverse transcriptase polymerase chain reaction (RT-PCR) from a buccal/oropharyngeal swab of the affected parotid duct within three days but not more than eight days after symptom onset. A negative serologic result, especially in a vaccinated person, should not be used to rule out a mumps diagnosis. In the absence of another diagnosis, a person with clinically compatible symptoms should be reported as a suspect mumps case.

For a list of commercial lab testing sites and reporting requirements please click here.

Please see the attached HAN Alert regarding mumps testing recommendations.  All cases of mumps (including suspected) must be reported to the Chicago Department of Public Health by calling (312) 746-5911, Monday-Friday between 8:30am-4:30pm. After hours, weekends, and holidays, call 311 and ask for the communicable disease physician on-call.